Free autogenous periosteal graft for repair of articular cartilage defects in rabbits morphological study.docVIP

 PAGE \* MERGEFORMAT 10 Free autogenous periosteal graft for repair of articular cartilage defects in rabbits morphological study [Abstract] [Objective] To observe and analyze free autogenous periosteal graft repair articular cartilage defects in rabbits the process of morphological changes. [Methods] In the 18 Chinese rabbits with bilateral femoral patellar surface making the size of 6.0mm * 3.0mm full-thickness articular cartilage defect model, line medial tibial periosteal graft, using microscopy and image analysis technique to observe surface of femur Patellar articular cartilage defects of the morphological changes. [Results] after the first 4 weeks, since the free periosteum group can be seen clearly cartilage lacuna and the homologous cell group, 12 weeks, cell density decreased matrix increased, close to the normal hyaline cartilage characteristics. autogenous free periosteal transplantation group at 4,8,12 weeks after operation the average area of individual cartilage cells compared with the control group were significantly different. [Conclusion] free periosteal autograft repairable articular cartilage defects, the process can be divided into cells proliferating, immature cartilage formation period and the transformation of cartilage shaping period in three phases. [Keywords:] Periosteal transplantation of autologous rabbit Study of morphological changes in repairing articular cartilage defects with transplanting autologous free periosteum ABSTRACT: OBJECTIVETo observe and analyze the process of morphological changes in repairing articular cartilage defects with transplanting autologous free periosteum.METHODSUsing the models of 6.0mm * 3.0mm of full thickness of articular cartilage defects on the patellar surface of femur established in 18 cases of knee joint of Chinese rabbits, the autologous free periosteum was transplanted into the facies medialis tibiae, and the morphological changes were observed in repairing articular cartilage defects with