GSTT Orally Disintegrating Tablets.docVIP

 PAGE \* MERGEFORMAT 13 GSTT Orally Disintegrating Tablets Of: Liangguo Cheng, Lu Jie, Lu Xiaohui, Zhou Yisheng [Abstract] Objective To screen the GSTT orally disintegrating tablets and the preparation process. Methods L9 (34) orthogonal test, the disintegration time as an index to microcrystalline cellulose, low substituted hydroxypropyl cellulose, cross-linked vinyl pyrrolidone, mannitol, etc. for the materials, the best prescription screening and preparation process. Results after optimization GSTT orally disintegrating tablet disintegration time is short, disintegration time of 25 s or so, taste good. Conclusions Oral GSTT disintegrating tablets meet the design requirements, the system method is simple, short disintegration time, taste good, easy to take. [Keywords:] GSTT; orally disintegrating tablet; orthogonal test Abstract: Objective To screen on the formulation and preparation process of orally disintegrating tablets of saponins from T. terrestris L. Methods The L9 (34) orthogonal was designed with disintegrating time as the assessment index, and MCC, L HPC, PVPP, Mannitol et al were used in the formulation and preparation.Results The optimum preparation showed a short disintegration time of about 25 seconds with a good taste.Conclusion Orally disintegrating tablets of saponins from T. terrestris L. were achieved, which had a very short disintegration time with a good taste and was easy to be prepared. Keywords:: Tribulus terrestris L.; saponin; orally disintegrating tablet; orthogonal Orally disintegrating tablet is 90 years abroad, the development of the 20th century, a new dosage form, with no water delivery service, without chewing, rapidly disintegrating in the oral cavity or dissolved, etc., for swallowing difficulties and poor self-medication of children and the elderly The patient was an ideal dosage form for oral administration [1]. Tribulus terrestris plants for the (Zugophyllaceae) Tribulus terrestris (Tribulus terrestris L