Gravity Determination of carbomer tablets peel adhesion of the relative.docVIP

Gravity Determination of carbomer tablets peel adhesion of the relative.doc

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Gravity Determination of carbomer tablets peel adhesion of the relative

 PAGE \* MERGEFORMAT 8 Gravity Determination of carbomer tablets peel adhesion of the relative [Abstract] Objective To establish the gravity stripping determination of the relative adhesion carbomer tablets, in order to provide a basis for adhesion of film studies. Method under test Carbopol film soaked in physiological saline, after a few minutes, take out, using dry filter paper and placed on a plexiglass sheet Ⅰ , Ⅱ and then covered with plexiglass piece to exert pressure, sustained a few minutes later, removed the pressure be Ⅰ plexiglass sheet hanging in the device, while plastic bags hanging in the plexiglass sheet Ⅱ on the importation of a certain flow to the plastic bag of water, weighing Ⅱ slides off, the plastic bag in the weight of the water, that is, Carbopol films for the relative adhesion. The results of orthogonal experiment to determine the adhesion of the determination method, and then the same batch of Carbopol 980 was determined adhesion results showed that the precision is 0.0255. Conclusion This method is simple, precision, and can be as Carbopol film adhesion of the determination of the relative one of the methods. [Keywords:] carbomer tablets; adhesion force; orthogonal design Establishment of peeling weight method measuring the relative adhesive force of carbopol tablet [Abstract] Objective To Establish the method of measuring the adhesive force of Carbopol tablets by qualifying the weight of water to separate the Carbopol tablets from organic glass. The exploring could provide the foundation for further study on the tablets.Methods A new apparatus made by ourselves was used to compare the adhesive force between the Carbopol tablets. In brief, soaked tablet was placed on organic glass Ⅰ , then glass Ⅱ and a heavy were on the tablet. After a while, the heavy was take away and water was added into the bottle linked on glass Ⅱ to make the tablet separate from glass. The weight of water in bottle was quantified as soon as the

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