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Gray Series Forecasting Model in the bone marrow stromal cells in vitro application
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Gray Series Forecasting Model in the bone marrow stromal cells in vitro application
【Abstract】 Objective: To investigate the in vitro bone marrow stromal cells (MSCs) during its passage into the bone after the induction of alkaline phosphatase (ALP) activity was studied. Methods: gray GM (1,1) model, in vitro passaged MSCs into the bone during and after the induction of ALP activity analysis and forecasting. Results: Gray GM (1,1) model in vitro passaged MSCs into the bone during and after the induction of ALP activity changes in high accuracy and reliable results. Conclusion: The in vitro passage of MSCs into the bone during and after the induction of ALP activity changes in the value of available gray GM (1,1) model for prediction.
Keywords: gray model of bone marrow stromal cell alkaline phosphatase
Bone marrow stromal cells (Marrow Stromal Cells, MSCs) is composed of many cells, groups composed of heterogeneous cell populations, during the existence of mesenchymal stem cells are a kind of self-renewal, replication and multi-differentiation potential of adult stem cells. MSCs osteogenic differentiation properties and closely related to the occurrence of osteoporosis, so in vitro induced MSCs and for their orientation in the prevention and treatment of osteoporosis in the pathogenesis of research in the field are widely used. Gray system GM (1,1) model is a continuous time differential equation model, because the model is not a general statistical model for various demands on the raw data constraints, thus has strong adaptability to predict good performance advantages, in the medical field has been widely applied. In this study, GM (1,1) model, MSCs and their orientation-induced alkaline phosphatase (alkaline phosphatase, ALP) to predict changes in the law is designed to gray GM (1,1) model for the further application of MSCs in vitro Culture provides a theoretical basis.
A model of principle and calc
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