Guangxi vine tea extract TTF anti-duck hepatitis B virus in experimental study.docVIP

 PAGE \* MERGEFORMAT 10 Guangxi vine tea extract TTF anti-duck hepatitis B virus in experimental study 【Abstract】 Objective To observe the tea from the Guangxi rattan extracted an effective part of TTF role of anti-duck hepatitis B virus. Elections of one-day-old ducklings Beijing, artificial infection of duck hepatitis B virus (DHBV) animal model, the application of the dot-blot hybridization observed TTF duck serum duck hepatitis B virus DNA (DHBV-DNA) effects. Results DHBV infected ducks in the first 7 days after infection TTF oral medication, 75 ~ 150 mg / kg group 2 times / d, 10 d for duck serum DHBV-DNA levels have a certain inhibitory effect; 300 mg / kg group, infected duck serum DHBV-DNA level of inhibition significantly, stopping 3 d no significant anti-jump phenomenon. Conclusions TTF could significantly inhibit the DHBV-DNA replication, suggesting that TTF has anti-HBV effect. Keywords: vine tea duck hepatitis B virus (DHBV) animal model of duck hepatitis B Abstract: ObjectiveTo investigate the anti-HBV effect of TTF.Methods1-day old Beijing ducklings were used as the hepatitis B animal model. DHBV DNA was detected by dot-blot hybridization test. ResultsAfter medicated with TTF for 5 days and 10 days, optical density value (OD value) of DHBV-DNA in ducklings sera was obviously lower than that before treatment, there were different influences in different groups and rebound phenomenon didn `t appear in both TTF-groups 3 days after stopping medication.ConclusionTTF is efficient in treating DHBV, which indicates that TTF has an anti-HBV effect. Keywords:: Teng cha; Duck hepatitis B virus; Duck hepatitis Model Vine Tea Department Vitaceae Ampelopsis species Ampelopsis Ampelopsis grossedentata (Hand-Mazz) WTWang of the Spear leaves, in Guangxi, Guangdong, Yunnan, Guizhou and Fujian are the distribution, also known as sweet tea vine, Tian Po Tea, Wu Lian, red cairica big tooth snake wine. Its sweet, light, sexual