HBsAg-positive hepatocellular carcinoma in serum HBV DNA levels after radical resection of hepatocellular carcinoma recurrence in.docVIP
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HBsAg-positive hepatocellular carcinoma in serum HBV DNA levels after radical resection of hepatocellular carcinoma recurrence in
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HBsAg-positive hepatocellular carcinoma in serum HBV DNA levels after radical resection of hepatocellular carcinoma recurrence in
Of: Cai pleased, Huang Changyu, Zhouhao Hui, Zhou Liang Yi
[Abstract] Objective To investigate the curative resection of hepatocellular carcinoma HBsAg positive in serum HBV DNA levels after the recurrence of hepatocellular carcinoma. Methods 72 HBsAg-positive hepatocellular carcinoma and underwent radical resection confirmed by pathology, detection after 1 , 3,6 on the serum HBV DNA level, liver function, recurrence and clinical pathological data and statistical analysis of the line. Results after different periods of serum HBV DNA levels were no significant differences (Pgt; 0.05, HBV DNA level , low, negative group the recurrence rate after 2 years and median time to recurrence was 70%, 45.57%, 36.36% and 14,34,41 months, the high and low, negative group there were significant differences statistically significant (P lt;0.01), multivariate COX regression analysis risk factors for liver cancer recurrence after portal vein tumor thrombosis, serum HBV DNA levels and tumor differentiation (P lt;0.05). Conclusion liver HBV DNA in serum after radical continued high levels are risk factors for liver cancer recurrence.
[Keywords:] liver tumor DNA Hepatitis B virus surface antigen of hepatitis B virus recurrence local tumor
Chronic hepatitis B virus infection and cirrhosis of the liver is our most important cause of primary liver cancer. Recent studies show that active replication of hepatitis B virus and hepatitis activity and liver cancer recurrence after resection is closely related to [12]. In this study, hepatitis B virus infection in patients with hepatocellular carcinoma after radical resection of serum HBV DNA levels and tumor recurrence.
1 Subjects and methods
1.1 The objects collected in January 2003 on December -2004 radical resection and primary liver cancer confirmed by pathology in 72
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