Horsehair snake alcohol extract of ovariectomized rats estrogen levels and blood lipid.docVIP

 PAGE \* MERGEFORMAT 8 Horsehair snake alcohol extract of ovariectomized rats estrogen levels and blood lipid Author: Lee on the ball, Zhao Jie, Li Ping, Xie Jin Xian [Abstract] Objective To study the ethanol extract of horse-hair snake (CVAE) in ovariectomized rats estrogen levels and serum lipid effects. Methods Surgical preparation of ovariectomized rats. CVAE gavage 21d. Radioimmunoassay of serum E2, FSH levels; by enzymatic determination of serum TC, TG content; microscopic observation of histopathological changes of the endometrium. Results CVAE high-and low-dose can be significantly increased serum E2 levels; CVAE high doses can reduce the serum levels of FSH and the TC will enable the rats exhibited estrus earlier than usual increase in organ coefficient of uterus; microscopic observation showed that, CVAE high-dose Groups of endometrial thickening, increased number of glands. Conclusion CVAE ovariectomized rats can be significantly improved to reduce the level of estrogen on lipid metabolism in ovariectomized rats disorder also have a certain improvement. [Keywords:] horsehair snake follicle-stimulating hormone, estradiol blood lipids Abstract: ObjectiveTo study the influence of Calotes versicolor Alcohol Extracts (CVAE) on the estrogen level and blood lipid in ovariectomy rats.MethodsThe ovariectomy female rats were made, then were treated with CVAE, ig, for 21 days. The levels of serum estradiol ( E2) and follicle stimulating hormone (FSH) were determined by the radio-immunoassay. The contents of serum total cholesterol (TC) and triglycerides (TG) were determined by enzyme technology.The histopathological change in mucous membrane was observed with microscope. ResultsThe low and high doses of CVAE significantly enhanced the level of E2. The high dose of CVAE decreased the level of serum FSH and the content of serum TC, made the phenomenon of rat oestrus be reserved beforehand, and increased the uterine coefficient. The microscopic examination res