HPLC Determination of pain and given halo of ferulic acid capsule.docVIP

 PAGE \* MERGEFORMAT 14 HPLC Determination of pain and given halo of ferulic acid capsule 【Abstract】 Objective: To establish a halo given the pain of ferulic acid in capsule HPLC quantitative determination. Methods: Shimadzu C18 column, methanol -0.5% glacial acetic acid (350:650) as mobile phase [1]; detection wavelength of 320nm [2]; flow rate of 1.2ml/min. Results: ferulic acid in the range of 0.0068 ~ 0.068μg good linearity, the regression equation Y = 5E 07X-63525, Г = 0.9983 (0.0068 ~ 0.068μg), recovery was 94.23%. Conclusion: This method is accurate, sensitive and convenient. Keywords: high-performance liquid chromatography dizzy pain, the amount of ferulic acid in capsule set Halo pain capsule is scheduled to Rendezvous Pharmaceutical Co., Ltd. Henan self-developed by the SFDA approval of the exclusive production of the anti-property protection migraine headaches, dizziness drug of choice. The current study results indicate that the solution of which Armillaria mycelial fermentation material with similar pharmacological effects of Gastrodia Rhizoma in the TMP and ferulic acid, the more obvious expansion of coronary artery, increase coronary blood flow and myocardial nutritional blood flow to heart for the oxygen increased, the promotion of myocardial oxygen supply and oxygen balance. In addition, its active ingredient ferulic acid, in vitro experiments show antithrombotic effects, can shorten the length of thrombus, reducing thrombus dry weight and wet weight. Currently the standard income-related drugs, goods contained in the “Ministry of Health, Drug Standards,” New Drug to positive standard (Volume II), which includes only the character identification and Armillaria fermentation culture and the qualitative identification of Chuanxiong. To play a major role in its pharmacological solution of Armillaria mycelial fermentation objects, TMP and ferulic acid by HPLC method has been established. Literature at home and abroad there is