Immunomagnetic technology applications in oncology.docVIP

 PAGE \* MERGEFORMAT 18 Immunomagnetic technology applications in oncology [Abstract] immunomagnetic microspheres is an immune, it is coated with monoclonal antibodies, spherical magnetic particles can be specifically combined with the target material so that a magnetic response can be separated to ensure that the target cells the integrity of form and function with high sensitivity, high specificity, detection speed, good reproducibility, simple and does not require expensive equipment, etc., in respect of this technology in the separation of tumor cells, accumulation and detection, and tumor biology and magnetic orientation treatment, Immunomagnetic purification of other areas of research reviewed in the paper. [Keywords:] immunomagnetic beads technique; circulating tumor cells; immunomagnetic purification; Summary [Abstract] Immunomagnetic beads, a kind of immunomagnetic microspheres, are the spherical magnetic particles coated with monoclonal antibodies, which can specifically combine with the target material and get magnetic responsiveness and ensure the morphological and functional integrity of the separated target cells. The higher sensitivity and specificity, rapid detection, well repeatability, easier operation and less expensive equipment requirement make this technique more popular. Immunomagnetic beads have gradually been applied to the separation, enrichment and detection of tumor cells, as well as to tumorous biological research and targeted therapy, immunomagnetic purification and other fields. [Keywords:] immunomagnetic beads; circulating tumor cells; immunomagnetic purification; review Immunomagnetic beads (immunomagnetic bead, IMB) technology is a new domestic and international research in recent years, immunological techniques. IMB is an immune microspheres, coated with monoclonal antibodies for the spherical magnetic particles, can be specific combined with the target material so that a magnetic response. The technology was de