In patients with chronic renal insufficiency determination of vasoactive substances in the blood purification in clinical research.docVIP

 PAGE \* MERGEFORMAT 9 In patients with chronic renal insufficiency determination of vasoactive substances in the blood purification in clinical research Author: Fan Yu-liang, Wang Mei-wen, Lu Yao, Zhang Kai-Xuan, Liu Qin, Xie Di, Jin Lei 【Abstract】 Objective To evaluate the angiotensin Ⅱ, carbamylated hemoglobin, aldosterone and parathyroid hormone in the blood purification such as the adequacy of the significance. 120 cases of chronic renal failure patients, according to a different dialysis membranes were divided into 3 groups: namely, polysulfone film, acetate film, copper film imitation. Were determined by radioimmunoassay of angiotensin Ⅱ (Ang Ⅱ) and aldosterone (ALD) concentration, chemiluminescence measurement of parathyroid hormone (PTH). Using different blood flow 200ml/min and 250ml/min comparison. The results in vivo, the small molecules clearance rate, polysulfone membrane “acetate film” Imitation of copper film. Conclusions high blood flow, high-permeability synthetic polysulfone membrane, chronic renal failure, renal insufficiency in patients with increased physical and mental health and quality of life and prolong life in patients with a very important clinical significance. Keywords: Chronic renal failure; angiotensin Ⅱ; aldosterone; parathyroid hormone; hemodialysis 【Abstract】 Objective Appraisal the significance of Ang Ⅱ, CarHb, ALD and PTH fix on clinical research of blood purification to reach the sufficient result.Methods 120 patients with chronic renal failure, according to adopt different dialysis membrane divide into three groups: namely polysulfone membrane , acetic acid membrane, cuprum imitate membrane.With immunoradiometric assays to determine their angiotensin Ⅱ (Ang Ⅱ) and aldosterone (ALD) density, chemistry iuminescence law, examine parathyroid hormone (PTH). Adopt different blood flow 200ml/min and 250ml/min compare . Results function on body by analysis the clearance rate of small nember material