In vitro induction of stem cells to differentiate into pancreatic β cells and study ways to Recent.docVIP

 PAGE \* MERGEFORMAT 14 In vitro induction of stem cells to differentiate into pancreatic β cells and study ways to Recent [Abstract] access to a recent study on the insulin-secreting cells (ISC) sources of relevant Chinese and foreign literature, suggesting that stem cells of the ISC as a major source of treatment of diabetes has become possible, an overview of the main source of stem cells induced to differentiate into pancreas of several β -cell pathway and Recent Research. [Keywords:] diabetes, stem cells, pancreatic β -cell synthesis Diabetes (diabetes mellitus, DM) is the major diseases affecting human health is one of decline in pancreatic endocrine β -cell function caused by insufficient insulin secretion and glucose metabolism disorders are major causes of diabetes in the study of pathogenesis at the same time, research islet cells functional state is one of the very important part. At present a number of tests to prove [1], pancreatic β -cell replacement therapy - islet cell transplantation is an effective way to cure diabetes. Due to a huge number of diabetic patients, the cell source of issues that must be resolved; and stem cells (stem cell, SC) as a class of multi-directional differentiation potential of cells, has gradually become a pancreatic β -cell substitutes the ideal resource. The traditional cell replacement therapy - the number of donor islet transplantation there is inadequate and immune rejection problem, and pancreatic stem cell transplantation is expected to overcome these shortcomings. In this paper, in recent years, access to the relevant Chinese and foreign literature, an overview of several induced to differentiate into pancreatic β -cell channels and Recent Research. An overview of stem cell In recent years, with improved immunosuppressive agents and cell transplantation technology continues to mature, and islet cell transplantation has become a cure for type 1 and type 2 diabetes, some of the preferred method of treatment.