Infected with hepatitis B virus pre-S1 protein detection and analysis of.docVIP

 PAGE \* MERGEFORMAT 6 Infected with hepatitis B virus pre-S1 protein detection and analysis of [Abstract] Objective: To observe the pre-S1 protein in the acute and chronic hepatitis B carriers in the different changes and to assess the prognosis of hepatitis B patient’s condition. Methods: A prospective cohort study methods, choice of 84 patients with different hepatitis B virus infection, according to pre-test interval of 0,1,3,6 on S1 protein, combined with liver function and clinical observation study. Results: The pre-S1 and HBV-related activities, has nothing to do with the hepatitis disease duration. Conclusion: The pre-S1 continuous positive hepatitis, hepatitis B virus carriers easy to attack. [Keywords:] pre-S1 protein of hepatitis B hepatitis B virus carriers A clinical data 1.1 General information on control group of 60 normal human blood samples from HBV-negative normal medical personnel detection. Group of 84 cases of HBV infection detected by key for me, out-patient or inpatient treatment area. Male and female ratio was 9:5 (54:30); aged 19 to 65 years old, an average of 35.14 ± 10.37 years. 1.2 Detection of HBV markers used ELTSA method (Shanghai Branch China Industrial Company, Ltd.), experiments carried out according to kit instructions. Pre-S1 protein, using double-antibody sandwich assay ELTSA, operations and results of determination by reference implementation of the kit instructions. Statistical methods, using χ test analysis. 2 Results 50 cases of normal serum pre-S1 of the test results were negative. 10 cases of acute hepatitis B patients pre-S1 () 8 cases, the detection rate was 80.0%, 44 patients with chronic hepatitis B patients pre-S1 () 30 cases, the detection rate of 68.2%, between the two was no significant difference ( Pamp;gt; 0.05). Recovering from hepatitis, acute hepatitis in patients with pre-S1 positive detection rate was 20.0%, pre-S1 in patients with chronic hepatitis positive detection rate of 18.1% between