Injection mezlocillin sulbactam treatment of pediatric infectious diseases clinical evaluation of.docVIP

 PAGE \* MERGEFORMAT 11 Injection mezlocillin sulbactam treatment of pediatric infectious diseases clinical evaluation of Abstract mezlocillin sodium and sulbactam sodium for enzyme production caused by drug-resistant respiratory infections, skin and soft tissue infections, and tonsillitis, severe infectious diseases, has absorbed quickly, a higher plasma concentration, plasma protein binding a higher rate of resistance to enzyme stability, antimicrobial broad spectrum efficacy, adverse reactions and so on. The main against Gram-positive bacteria, Gram-negative cocci and Actinomyces bacteria are highly sensitive. Of its antibacterial activity, primarily by interfering with bacterial cell wall synthesis, can inhibit bacterial cell wall synthesis of growing season, but also to promote the decomposition of the cell wall, leading to bacterial death. 【Key Words】 infections / diagnosis; mezlocillin / therapeutic use; Antibiotics / administration and dosage; children Mezlocillin sodium and sulbactam sodium-containing β  lactamase inhibitors - sulbactam, for drug-resistant enzyme production caused by moderate to severe infectious diseases, has absorbed quickly, a higher plasma concentration, plasma a higher rate of protein binding, resistance to enzyme stability, antimicrobial broad spectrum high efficacy [1], fewer adverse reactions and other characteristics of the clinical treatment of children with a variety of infectious diseases, a good drug. An antibacterial effect 1.1 Antibacterial spectrum of mezlocillin sodium and sulbactam sodium, is a Penicillium broad spectrum antibiotics, mainly against Gram-positive bacteria, Gram-negative cocci and Actinomyces bacteria are highly sensitive, such as staphylococcus, streptococcus, and pairs of bacteria, etc. highly sensitive; pairs of Corynebacterium diphtheriae, Bacillus anthracis, Clostridium sp teeth, cattle actinomycetes, and got the ball chain of bacilli, mononucleosis Xing Li Divi