Kang TB TB model in mice immune parameters observed.docVIP

 PAGE \* MERGEFORMAT 8 Kang TB TB model in mice immune parameters observed Of: Pin-liang Shen Jingui Ye Shuai Lu Runsheng Block Wei Ying [Abstract] TB Kang (FLK) on experimental tuberculosis immune parameters observed in mice to study the immune regulation of anti-TB tuberculosis health role for health treatment of tuberculosis and provide experimental evidence of tuberculosis. [Method] after the model animals were randomly divided into high-dose group FLK, FLK middle dose group, rifampicin group, a separate control group were given health tuberculosis, rifampicin, saline 28 days to observe the thymus index of mice, T lymphocyte subsets, IFN r, IgG change the situation. [results] FLK high dose significantly increased the thymus index of mice (P lt;0.05, FLK high dose group the number of CD4 + T cells increased significantly (P lt;0.01, P lt;0.05, CD8 + in each group between the difference was not statistically significant (Pgt; 0.05, model group, CD4 + / CD8 + ratio was significantly lower, the difference was significant (P lt;0.01), FLK high dose group significantly reduced CD4 + / CD8 + ratio decreased, the difference was significant ( P lt;0.01), FLK high dose group increased plasma IFN r mouse model of tuberculosis and IgG levels (P lt;0.05). [Conclusion] TB Kang obvious role of anti-TB immune regulation. [Keywords:] TB Kang, tuberculosis, immune function Abstract: [Objective] To study the function of Feilaokang (FLK) in immune regulation and anti tuberculosis by observing the experimental mice immune indexes, offer experimental base for its treating lung tuberculosis. [Method] Randomly divide mice into groups of FLK in high dosage , middle dosage and Lifuping group, set another blank control group, respectively give them FLK, Lifuping and normal saline for 28 days, observe their thymus index, T sub lymphocyte, IFN r and IgG. [Result] The high dosage group can markedly increase thymus index, as well as CD4 + and T cell, there’s no marked differe