Line intraluminal middle cerebral artery occlusion induced focal cerebral ischemia-reperfusion rat model of cerebral edema and cerebral infarction than the changes in.docVIP

 PAGE \* MERGEFORMAT 9 Line intraluminal middle cerebral artery occlusion induced focal cerebral ischemia-reperfusion rat model of cerebral edema and cerebral infarction than the changes in Author: Juan-juan Zhao Guo-Ping Ke Tang Jun Huang Juan Li Li Keywords: middle cerebral artery occlusion; focal cerebral ischemia / reperfusion; cerebral edema; Abstract: Objective: To investigate the short-term nature of the right middle cerebral artery occlusion induced focal cerebral ischemia-reperfusion model of cerebral infarction and brain edema compared with the changes. Methods: The suture method produced cerebral ischemia / reperfusion models at different time points, line measurement of cerebral infarction compared with TTC staining and measurement of brain water content of wet and dry weighing method. Results: 6h cerebral ischemia and reperfusion in rat brain tissue that is when the water content increased, and as time goes on the rise, and did not damage brain tissue adjacent to the middle of the most significant increase in water content. TTC staining in ischemia-reperfusion 6h, you can see a white infarction, infarct reperfusion than in a gradual increase within 72h. Conclusions: Focal cerebral ischemia-reperfusion 72h and brain edema in cerebral infarction than Juncheng sexual increase. Keywords:: middle cerebral artery occlusion; focal cerebral ischemia / reperfusion; cerebral edema; Cerebral infarction than in ischemic brain injury (ischemia brain injury) is the provision of life-threatening diseases. The cerebral ischemia and reperfusion induced cerebral edema (hydrocephalus) that affect patients with acute and sub-acute phase of the survival of important factors. Larger area of ischemic lesion due to cerebral edema caused by a sharp increase in volume of brain tissue, can induce brain herniation. Ischemic brain edema after cerebral ischemia is considered to aggravate the existing disease, leading to patients with life-threatenin