Levofloxacin Hydrochloride Injection 1 case of adverse reactions caused by.docVIP

 PAGE \* MERGEFORMAT 3 Levofloxacin Hydrochloride Injection 1 case of adverse reactions caused by [Keywords:] side effects levofloxacin 1 Case Summary Cao Moumou patients, female, 58 years old, suffering from acute gastroenteritis on July 15, 2009 to our hospital, giving Levofloxacin Injection (meditation on Pharmaceutical production, batch number size 100ml: 0.3g) intravenous drip Note, 40 drops / min.2 minutes later, the patients chest tightness, shortness of breath, palpitation, dizziness, hands, lower extremity numbness and other symptoms, blood pressure 110/60 mmHg, heart rate 67 times / min, breathing 18 times / min, body temperature 36.8 ℃, immediate withdrawal, intravenous injection of dexamethasone 5 mg, oxygen, to give 100 mL of 0.9% sodium chloride 5mg intravenous dexamethasone, 20 minutes after the symptoms slightly improved but remains palpitation, dizziness, again given intravenous injection of dexamethasone 5 mg, continuous oxygen, and 30 minutes later, the patient the symptoms disappeared. readme patients with no history of drug allergy, 1 week before admission, have not used other drugs. 2 Discussion Levofloxacin (1evofloxacin) is levo ofloxacin, is a third-generation fluoroquinolones. Its broad antimicrobial spectrum, strong antibacterial activity on Gram-negative bacteria has a strong antibacterial activity against Gram-positive bacteria and Legionella, mycoplasma, chlamydia has good antibacterial activity, but the role of anaerobic bacteria and enterococci poor. may, by oral and intravenous administration and rapid distribution into the body of the organization. The main mechanism for the inhibition of bacterial DNA gyrase (bacterial topoisomerase Ⅱ activity, impede bacterial DNA replication, for urinary tract infections caused by sensitive pathogens, prostatitis, gonorrhea, respiratory infections, various infections caused by gram-negative bacilli and bone, joint and soft tissue infections [1]. the drug in recent years b