Marker CD41 stained small megakaryocytes in elderly patients with anemia diagnosis.doc

 PAGE \* MERGEFORMAT 12 Marker CD41 stained small megakaryocytes in elderly patients with anemia diagnosis Of: Xing Ying, Qu Yan, Huang Jialing, Lin Shudong [Abstract] Objective: To evaluate the CD41 marker staining small megakaryocytes (SAP stain) of anemia in the elderly in the diagnosis and differential diagnosis. Methods: The Reiter Giemsa staining and CD41 staining SAP markers were detected 107 cases of anemia in patients aged 60 or older in the tiny smears of bone marrow megakaryocyte number and type. Results: CD41 staining of SAP labeled megakaryocytes was higher than that Reiter Giemsa staining, the two-phase statistically significant difference compared (P lt;0.01). different disease groups, small positive rate of MDS megakaryocytes was the highest, followed by MDSgt; ITPgt; MAgt; ACDgt; MMgt; IDAgt; RAgt; AAgt; PRCAgt; CAA; lymphoid MDS group of small megakaryocyte detection rate of 73.6%, other groups were not detected. Conclusion: CD41 staining SAP markers can significantly improve the detection rate of megakaryocytes; and anemia in the elderly has a differential diagnosis. [Keywords:] CD41 monoclonal antibody; small megakaryocyte; SAP staining; older anemia; differential diagnosis [Abstract] Objective: To assess the significance of the CD41 labelled micromegakaryocyte Streptavidin Alkaline Phosphatase (SAP) staining in the diagnosis and differential diagnosis of senile anemia. Methods: Bone marrow smears from 107 patients with anemia over the age of 60 were detected by Wright Giemsa staining and CD41 labelled SAP staining for the number and types of micromegakaryocytes, respectively. Results: The detection rates of megakaryocyte by the CD41 labelled SAP staining and Wright Giemsa staining had significant difference (P lt;0.01). Among the groups, MDS group for the positive rate of micromegakaryocyte ranked the first, followed by ITPgt; MAgt; ACDgt; MMgt; IDAgt; RAgt; AAgt; PRCAgt; CAA; Detection rate of lymphoid micromegakaryocyte in the