Maternal serum hepatitis B virus large protein molecules in the meaning of mother to child transmission.doc

 PAGE \* MERGEFORMAT 6 Maternal serum hepatitis B virus large protein molecules in the meaning of mother to child transmission [Abstract] Objective To detect the hepatitis B virus in pregnant women with hepatitis B surface antigen large protein (LHBs, neonatal serum HBsAg, reveals the LHBs in the clinical significance of mother to child transmission. Methods Using enzyme-linked immunosorbent assay (ELISA for HBsAg for LHBs and testing. The results were 312 cases of hepatitis B LHBs pregnant women and their newborns HBsAg test results showed: hepatitis B patients with different women LHBs, newborn infection rates were significantly affected (P lt;0.01). Conclusion LHBs to reflect the strong maternal infectious weak, then estimated HBsAg-positive pregnant woman’s risk of fetal intrauterine infection in high and low. [Keywords:] mother to child transmission of hepatitis B virus large surface protein of hepatitis B surface antigen China is a high incidence of hepatitis B, hepatitis B virus mother to child transmission is the major route of transmission in infants of about 1 / 3, also contributed to the popularity of the main factors of hepatitis B [1]. Hepatitis B virus large protein molecule ( LHBs) present in infectious particles (Daue particles) and sub-viral particles on the tube, is a virus an important indicator of a complete membrane, and serum HBV DNA copy number with a good correlation, can reflect the body in patients with hepatitis B virus replication [ 2]. In many of our primary health care units, can not detect HBV DNA, HBV replication levels in pregnant women is difficult to determine. This testing of pregnant women and fetal cord blood serum HBsAg, LHBs, and analyze their relevance to further clarify the maternal serum HBV virus large surface protein and the relationship between intrauterine infection and reduce the incidence of HBV. 1 Subjects and methods 1.1 The object of study from April 2008 to April 2010 in our hospital 31