Mechanical ventilation in patients with severe organophosphate poisoning of.doc

 PAGE \* MERGEFORMAT 7 Mechanical ventilation in patients with severe organophosphate poisoning of Emergency department of our hospital from January 1997 to April 2008 were treated in acute severe organophosphorus pesticide poisoning, 188 cases of patients, which took place were 120 cases of acute respiratory failure, 80 patients cured by conventional therapy, conventional treatment of the remaining 40 cases ineffective use of artificial respiratory support both technologies, cured 38 cases, 2 deaths, due to mechanical ventilation technology of organic phosphorus pesticide poisoned patients can be significantly improved survival rate, are reported below. 1 Clinical data Control group: from July 1991 to December 1996 admitted to college by severe organophosphorus pesticide poisoning cases, 210 cases, 76 males and 134 cases of women aged 15 to 75 years, all cases of oral organophosphorus insecticide poisoning. Among them, 91 cases of parathion poisoning, 110 cases of poisoning omethoate other 9 cases of organophosphate insecticide poisoning. 96 cases of acute respiratory failure, 81 patients with central respiratory failure, respiratory failure induced intermediate syndrome 15 cases, 173 cases were cured, 37 patients died, 35 patients died of respiratory failure, 2 patients died of cardiac arrest, with a total cure rate of 82.3% , the total mortality of 17.7%. Group therapy: as early as possible the elimination of toxins, including vomiting, gastric lavage, catharsis and cleaning of contaminated skin, hair and clothing. The early use of cholinesterase agent, rational use of anticholinergic drugs, give those who have breathing difficulties oxygen, the brain edema associated with timely application of dehydration and diuretics, while strengthening the support and symptomatic treatment, but the group did not use artificial breathing technique. Treatment group: January 1997 to April 2008 all acute severe organophosphorus pesticide poiso