Medical ozone on rabbit knee joint fluid SOD MDA contents of.doc

 PAGE \* MERGEFORMAT 10 Medical ozone on rabbit knee joint fluid SOD MDA contents of [Abstract] Objective: To explore the medical ozone on rabbit knee joint fluid superoxide dismutase (SOD), malondialdehyde (MDA) content. Methods: 30 rabbits were randomly divided into 3 groups: normal the control group (N), model group (M), ozone treatment group (O), n = 10. M, O group were modeling the first 1,4 days after injection of the right knee joint cavity 0.3 1.6% papain solution ml preparation of osteoarthritis (OA) model. After the modeling, the first 3,5 days to the O group of the right knee joint cavity of animals injected with 20 g / ml of medical ozone 3 ml. 1 week after the last injection of extract from the right knee Determination of joint fluid SOD, MDA content. Results: Compared with the N, M group content of joint fluid in the lower SOD, MDA content increased; compared with the M, O group in the joint fluid increased the content of SOD, MDA levels are low. The differences were statistically significant (P lt;0.05). Conclusion: The intra-articular injection of 20 g / ml of ozone for medical treatment of knee osteoarthritis in rabbits may be related to enhance the body remove free base capacity. [Keywords:] ozone; osteoarthritis; superoxide dismutase; malondialdehyde [Abstract] Objective: To observe the effect of medical ozone on superoxide dismutase (SOD) and malondialdehyde (MDA) in the douche fluid of osteo arthritic knee joint in rabbits. Method: Thirty adult New Zealand white rabbits were randomly divided into three group: group normal (N), group model (M), group ozone (O), each group had ten rabbits. OA modle was produced by injecting 0.3 ml of 1.6% papain solusion into the right knee joint space twice three days apart. 3ml of O3 20 g / ml was injected into the right knee joint in group ozone on the 3rd and 5th day after OA modal was established successfully. One week later the last injection, douche fluid of the diseased joints were obtained f