Methods of myocardial protection during cardiopulmonary bypass Progress.doc

 PAGE \* MERGEFORMAT 16 Methods of myocardial protection during cardiopulmonary bypass Progress [Keywords:] myocardial protection, cardiopulmonary bypass Myocardial protection of origin in 1950, Big-elow proposed general protective effect of hypothermia on the heart, 1960, Shumway and Lower, respectively, reported the local cardiac protective effect of hypothermia on the heart, Mel-rose also proposed cardioplegia technique, 1978 Stthomas solution to myocardial protection techniques become mature, to bring about a leap in cardiac surgery. the mid-80s last century, the rise of a beating heart myocardial protection techniques, myocardial protection technology since the research is still ongoing and the development of myocardial protection generous reading from a simple intraoperative myocardial protection into preoperative, intraoperative and postoperative myocardial comprehensive protection. This article will, and myocardial protection methods were reviewed in general, for reference. 1 cardioplegia perfusion 1.1 antegrade perfusion antegrade coronary perfusion or perfusion via aortic root is the most commonly used perfusion for most of the open heart surgery. Usually in the aortic root perfusion, coronary artery can also be bridge or vascular perfusion. while pieces of ice placed around the heart, so that the local temperature at about 4 ℃, the heart rapidly cooled cardioplegia perfusion pressure should not exceed 26.7 kPa, infusion rate 250 ~ 300ml/min, perfusion l0 ~ 20ml/kg. Advantages : can more precisely the myocardial perfusion cardioplegia. Disadvantages: Too Assembly perfusion pressure and coronary artery damage along the walking paths lead to ischemic myocardial injury. 1.2 Retrograde coronary sinus retrograde perfusion referred to as retrograde perfusion [1], was first proposed by the Lillehei1956 1978 1982 Menaehe Solorzano and the technology used in clinical indications that have to adapt to the aortic valve insufficiency and patients w