Metoprolol in the treatment of clinical observation and analysis of coronary heart disease.docVIP

 PAGE \* MERGEFORMAT 2 Metoprolol in the treatment of clinical observation and analysis of coronary heart disease [Keywords:] Clinical observation of metoprolol in coronary heart disease Authors from January 2004 to October 2008 with metoprolol in the treatment coronary heart disease, hypertension, atrial fibrillation with heart failure in 45 patients to observe the clinical efficacy, are reported below. A clinical data 1.1 General information on 45 cases of rapid atrial fibrillation were hospitalized for coronary heart disease, high blood pressure or heart failure patients, male 24 cases, female 21 cases; the average age of 67.5 years. New York Heart Association (NYHA) classification 21 cases of grade Ⅲ , Ⅳ grade 24 cases, LVEF was 25% ~ 50%, persistent AF 1 ~ 15 years. In all cases there was no atrioventricular block, hypotension, asthma, β -blocker use contraindication. Conventional given diuretics (furosemide). 1.2 treatment of metoprolol 12.5 ~ 25mg / times, 1 ~ 2 times / d, depending on condition and degree of tolerance in patients with double dose of a week to 25 ~ 50mg / times, 1 ~ 2 times / d, other treatments constant. If medication during the non-congestive heart failure, hypotension and shock, allergies or asthma, slow arrhythmias can long-term use. 1.3 determine the efficacy of the standard resting heart rate were measured before and after treatment, blood pressure, LVEF, cardiac function and ECG changes in the situation. Markedly effective: After treatment, improvement of cardiac function grade Ⅱ ; effective: After treatment, improvement of cardiac function 1; invalid: no improvement in cardiac function. Determined by ECG effects [1] standard, effective in: ischemic ST segment of basic recovery, or the same lead before and after treatment, depressed ST segment recovery