Middle aged patients with lower respiratory tract infection within the extended spectrum monitoring of Escherichia coli and resistance.doc

 PAGE \* MERGEFORMAT 7 Middle aged patients with lower respiratory tract infection within the extended spectrum monitoring of Escherichia coli and resistance Of: Lin Wang Xin talent topaz flower blossoms [Keywords:] producing extended spectrum -lactamase, Escherichia coli, nosocomial infection, drug resistance Currently, the hospital infection of gram-negative pathogens are still (G-) bacilli (1,2), the most common is Escherichia coli. Elderly patients more than the underlying disease, longer duration, due to low immunity, etc. G-susceptible bacilli. This in our hospital from 2007 to 2008 in elderly patients with lower respiratory tract infection isolated 401 strains of E. coli, with the double disc synergy test and the confirmatory test for detection of extended-spectrum -lactamase (ESBLs ), and a drug sensitivity test, the lower respiratory tract infections in elderly resistance of Escherichia coli producing ESBLs, as the old lower respiratory tract infection Escherichia coli producing ESBLs provide the basis for rational use of antibiotics. 1 Materials and methods 1.1 The sources and identification of strains Our hospital from January 2007 to December 2008 of elderly hospitalized patients with lower respiratory tract infection Escherichia coli isolated from 401, male 217 cases, 184 cases of women aged 61 to 83 years (mean 71.2 + -5 years. lower respiratory tract specimens, including sputum, bronchoalveolar lavage, bronchoscopy seized under anti-pollution materials such as hair brush. strain identification using automated microbial identification system VITEK2 (Bio Merieux, France). Escherichia coli standard strain ATCC25922. 1.2 Determination of enzyme production strains Producing ESBLs were screened by double disc synergy, and with the National Committee for Clinical Laboratory Standards (CSLI recommended confirmatory test validation. 1.3 The sensitivity test Determined by agar disk diffusion method of Escherichia coli producin