Midazolam for elderly patients with acute myocardial infarction in patients with sedative hypnotic efficacy analysis.doc

 PAGE \* MERGEFORMAT 12 Midazolam for elderly patients with acute myocardial infarction in patients with sedative hypnotic efficacy analysis Author: Cheng Chen Zeng-Rui weeks of caring for sunrise Gan CHEN Mei-xia HUANG Xi-Tong Li Xiao-Min Hung [Abstract] Objective To evaluate the midazolam for the acute phase of myocardial infarction in elderly patients with sedative effects and side effects. Methods 42 cases of more than 60 years of age hospitalized with acute myocardial infarction were randomly divided into two groups, each 21 cases, respectively, taking midazolam (noon to take 3.75 ~ 7.5mg, bedtime 7.5 ~ 15mg) and diazepam (daytime hours twice taking 2.5 ~ 5.0mg, bedtime 5.0 ~ 7.5mg), so that patients achieve the level of sedation ramsary score 2 to 3 minutes. Every 6 hours a time record level of sedation to achieve sedation requirements in mind one points short of the required points were recorded 0; incidence of 7 ~ 10d using clinical mental health symptom checklist (SCL-90) evaluation. The results of midazolam group and the diazepam group, respectively (0.42 ± 0.25) h and (1.11 ± 0.46) h begun to reach sedation The difference was statistically significant (t = 3.22, P amp;lt;0.05). Midazolam sedation in mind is divided into groups (24.63 ± 5.31) points, diazepam group (18.21 ± 4.52) points, the former significantly larger than the latter (t = 2.54, P amp;lt;0.05). Patients with SCL-90 assessment, the midazolam group of somatization, compulsion, depression, anxiety, terror and mental factor score was significantly lower than the diazepam group (t = 2.07,2.12,2.23,2.07,2.15,2.17 respectively , P are amp;quot;0.05). Conclusion midazolam for myocardial infarction in the elderly than the sedative and hypnotic effect of diazepam effect faster, lethargy, fatigue, anorexia, depression, anxiety symptoms than diazepam, more suitable for patients with myocardial infarction in the elderly. [Keywords:] Midazolam; diazepam; acute myocardial infarction Abstract