Mild head injury patients in the NSE and S-100B and its significance.doc

 PAGE \* MERGEFORMAT 7 Mild head injury patients in the NSE and S-100B and its significance Of: Zhou Qingfeng, Shang Dingkun, full dragon, Hu Xin [Abstract] Objective: To investigate the mild head injury patients neuron-specific enolase (NSE and S-100B and its clinical significance. Methods: Determination of ELISA test score of 97 cases of 13 Glasgow 15 sub-head injury patients and 30 normal human serum NSE, S-100B levels. Results: The patients with a history of coma after the injury within 24 h of serum NSE, S-100B concentrations (13.08 +-3.15g / L and (0.76 +-0.13g / L, were significantly higher than those without a history of coma patients (6.73 +-2.11g / L, (0.181 +-0.039g / L and normal control group (5.95 +-1.71g / L , (0.167 +-0.031g / L (P lt;0.01, no history of coma patients and normal control group, no significant difference (Pgt; 0.05. Conclusion: The serum NSE, S-100B reflects the detection of brain damage circumstances, can be used as mild head injury patients without brain damage signs of a test, there is a history of coma, often accompanied by mild head injury patients with brain damage. [Keywords:] mild head injury S-100B protein in neuron-specific enolase Mild head injury usually refers to the Glasgow score was 13 to 15 minutes, there is no history of unconsciousness or coma a short time, neurological examination no signs of organic damage, brain imaging studies and no abnormalities found in head trauma. Which coma, often with a history of memory disorder, we call it a concussion (brain concussion, the traditional view is that their organizations were no significant morphological changes. in recent years the mechanism of brain concussion and brain structure changes in many studies and a new understanding, the majority of scholars believe that the current system of a mild brain concussion, axonal injury, there are some pathological changes in brain tissue can cause biochemical changes. we passed on, including the 97, including concus