Misoprostol for prevention of postpartum hemorrhage.doc

 PAGE \* MERGEFORMAT 9 Misoprostol for prevention of postpartum hemorrhage [Abstract] Objective To observe the misoprostol vaginal delivery (natural labor to prevent postpartum hemorrhage in the safety and effectiveness. Methods February 2005 to April 2008 mothers giving birth in our hospital, select the normal full-term pregnancy, childbirth , single cephalic, no complications or complications of pregnancy, prostaglandin inhibitors have not used the natural parturients were randomly divided into the misoprostol group and oxytocin group, early in the third stage of labor were given misoprostol in the forefront anus alcohol or intravenous oxytocin, measured postpartum 2 h, 24 h blood loss, monitoring of maternal postpartum blood pressure, pulse, and adverse reactions. misoprostol results in 2 h and 24 h post-partum bleeding was significantly lower than oxytocin group (P lt;0.05, and maternal postpartum blood pressure, pulse, no significant changes (Pgt; 0.05. Conclusion misoprostol is safe, simple and efficient role in the prevention of postpartum hemorrhage, reducing maternal mortality and reducing blood transfusion with a volume of great significance. [Keywords:] misoprostol for postpartum hemorrhage prophylaxis oxytocin [Abstract] Objective To investigate the effects and the safety of misoprostol on prevention and treatment of postpartum hemorrhage.Methods Eighty-four normal parturients were randomized into two groups: misoprostol group and oxytocin group, respectively given oral misoprostol and 20 IU oxytocin injected into muscle in the third stage of labour, the amount of bleeding within 2 h and 24 h after delivery was measured, and side effect, pluse, blood pressure changes were observed.Results The mean amount of bleeding in misoprostol group was significantly lower than oxytocin group ( P lt;0.05.Conclusion Misoprostol is safe, easy and effective in prevention of postpartum hemorrhage. [Keywords:] postpartum hemorrhage, misoprostol, oxytocin,