网站大量收购独家精品文档,联系QQ:2885784924

Multi-channel multi-stage cervical cancer evolution tree model construction.doc

Multi-channel multi-stage cervical cancer evolution tree model construction.doc

  1. 1、本文档共6页,可阅读全部内容。
  2. 2、原创力文档(book118)网站文档一经付费(服务费),不意味着购买了该文档的版权,仅供个人/单位学习、研究之用,不得用于商业用途,未经授权,严禁复制、发行、汇编、翻译或者网络传播等,侵权必究。
  3. 3、本站所有内容均由合作方或网友上传,本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺!文档内容仅供研究参考,付费前请自行鉴别。如您付费,意味着您自己接受本站规则且自行承担风险,本站不退款、不进行额外附加服务;查看《如何避免下载的几个坑》。如果您已付费下载过本站文档,您可以点击 这里二次下载
  4. 4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等,请点击“版权申诉”(推荐),也可以打举报电话:400-050-0827(电话支持时间:9:00-18:30)。
查看更多
Multi-channel multi-stage cervical cancer evolution tree model construction

 PAGE \* MERGEFORMAT 6 Multi-channel multi-stage cervical cancer evolution tree model construction Author: Liu takeoff, Huang Zhong Xi, Zhi-Hua Yin, Kai-Tai Yao [Abstract] Objective-based comparative genomic hybridization of cervical cancer information cervical cancer to build a tree model to explore the evolution of cervical cancer development in multi-channel mode. Methods According to the complete collection of 58 cases of cervical cancer comparative genomic hybridization data, such as the use of established tumors Desper tree model software platform to build a tree model of cervical cancer. Cervical tree model results suggest that there are six non-random chromosomal amplification or deletion occurred in the course of cervical change: 1q, 3q, 5p, 17q, 20q, and 20p, which 3q and 1q may be important in cervical cancer an early event; 3q first place in 17q, and that may exist between the two has dependencies; and, 1q may be a relatively independent events; these amplified chromosome that may exist and cervical cancer occurrence and development are closely related to the evolution of oncogene. Conclusion is based on comparative genomic hybridization data to build a tree model of cervical cancer, suggesting that multi-stage cervical cancer, multi-channel evolution model of development, but also for the follow-up of cervical cancer-related genes indicate the direction of exploration. [Keywords:] cervical cancer; comparative genomic hybridization; tree model Abstract: Objective Based on CGH (comparative genomic hybridization, CGH) data, to construct tree model of cervical carcinoma and to explore multipathway model of cervical carcinoma progression. Methods Using the software which Desper et al developed, tree models of cervical carcinoma were constructed according to the CGH data of 58 cervical carcinoma patients. Results Tree models for cervical carcinoma suggested that there were 1q, 3q, 5p, 17q, 20q and 20p six nonrandom genetic events, and 1q and 3q might

文档评论(0)

jiupshaieuk12 + 关注
实名认证
内容提供者

该用户很懒,什么也没介绍

版权声明书
用户编号:6212135231000003

1亿VIP精品文档

相关文档