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Naloxone combined Qingkailing acute severe traumatic brain injury Efficacy
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Naloxone combined Qingkailing acute severe traumatic brain injury Efficacy
Author: Yan-Indian roots Liu Xiaolong Wei Dai Yu Haisheng
[Abstract] Objective To investigate the joint Qingkailing naloxone in acute severe brain injury in the application results. Methods 94 patients were randomly divided into two groups on the basis of conventional treatment control group received naloxone injection; treatment group received naloxone injection and Qing Kai Ling Injection. Results In the treatment group, the total effective rate was 97.9% in the control group, the total effective rate was 93.3%, the total effective rate difference between the two groups was significant (P amp;lt;0.05). Compared two groups of awake time also have significant differences (P amp;lt;0.05). Conclusion The combination of naloxone and Qingkailing the treatment of acute severe traumatic brain injury compared with naloxone alone group to better efficacy of the role and has a better wake-up.
[Keywords:] of acute severe traumatic brain injury Naloxone Qingkailing
Naloxone is a competitive in vivo opioid receptor antagonist, can regulate the endocrine activities to improve blood flow dynamics and micro-circulation, reduce secondary brain injury and promote recovery of neurological function and improve prognosis. Qing Kai Ling Injection Angongniuhuang Pill in traditional Chinese medicine made on the basis of a new restructuring preparation, with heat phlegm, blood stasis and Tongluo, Xingnao resuscitation and so on. I Affiliated Hospital of brain surgery since 2006, the combination of naloxone and Qingkailing treatment of patients with acute severe traumatic brain injury, 49 patients satisfied the clinical efficacy, are reported as follows.
A basic information object of study
Since 2006, admitted 94 cases of acute severe head injury patients, male 69 cases, female 25 cases; aged 15-71 years, mean age (39.14 ± 19.13). GCS (glasgow scale) score at 3-8, with an average (5
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