Nano Pearl Powder on rats with deep Ⅱ ° burn wound healing.doc

 PAGE \* MERGEFORMAT 10 Nano Pearl Powder on rats with deep Ⅱ ° burn wound healing Author: Cui Shufang, Hao glorious, Tom Ball, Sun Wei, CAO Ping 【Abstract】 Objective To study the nanometer pearl powder on rat deep Ⅱ ° burn wound healing effects of pearl powder with micron carried out in burn healing efficacy comparison. Methods nano pearl powder, pearl powder micron (0.5g / only) were prepared with the glycerin into a mixture of 1:1. Micron pearl powder group and the natural healing group as control, nano pearl powder group, experimental group. Determination of 14% in rat deep Ⅱ ° 7,15,21 days after burn wound healing rate, wound histological and skin hydroxyproline content. The results of nano pearl powder group, the wounds healing rates over the micro pearl powder group, the high natural healing group (P lt;0.05 or P lt;0.01); burn the skin of each group after 3 days of hydroxyproline content were lower than normal (P lt;0.01) , nano pearl powder groups than other groups to reduce the degree; 5 days after injury, some recovery in each group HP content, especially in nano pearl powder was significantly higher than that of natural healing group and micro pearl powder group; 10 days each group was significantly l high, while the nano pearl powder group differences in HP content increased very significantly (P lt;0.01). Conclusion nano pearl powder can promote the rat deep Ⅱ ° burn wound healing, the healing was significantly higher than micrometer pearl powder (P lt;0.05). Keywords: nano pearl powder; micrometer pearl powder; burns; hydroxyproline 【Abstract】 Objective To study the efficiency comparison between nano and micro pearl powder for treatment of deep Ⅱ ° skin scalds in rats.Methods Nano and micro pearl powder (0.5g each rat) are mixed with glycerol (1:1). With the micro pearl powder group and the normal healing group as the control, nano pearl powder were used as drug on the deep Ⅱ ° skin scalds of rats in the experimen