Neonatal giant cell disease 3 cases of adrenal.doc

 PAGE \* MERGEFORMAT 6 Neonatal giant cell disease 3 cases of adrenal [Keywords:] Giant Cell Disease of adrenal Giant cell disease of adrenal (anrenal cytomegaly is a very rare congenital disease, the domestic rarely reported. Histology of cortical cells in the fetal cell size, shape and cell structure, changes its characteristics. 3 cases are reported, with the literature and their clinical and pathological diagnosis of the characteristics discussed. 1 Clinical data 1.1 General Information Hospital 1987-2007 detected 367 cases of neonatal autopsies in newborns 3 cases of cytomegalovirus disease. Case 1: male, full-term pregnancy, caesarean section because of fetal distress line delivery, birth weight 2 250g, raw the day after, the skin jaundice, poor mental reaction, the condition becoming critical, sallow, shortness of breath, 60 times / min, three depressions sign (+, limb hypotonia, continuous oxygen and no relief, chest radiograph showed return of “bronchial Yan “, blood WBC 7.9 109 / L, suspected intrauterine infection, and the family to give up treatment. Case 2: male, 32 weeks gestation, birth weight 1 650g, 10 minutes after birth, there is a transient RDS, breathing 120 times / min, heart rate 180 beats / min, 3 days after birth, systemic scleroderma 2 days, increased significantly, died of respiratory failure. Case 3: female, 32 weeks pregnant, twins eldest daughter, 1 500g, 4 to 6 hours after birth respiration sexual difficulties, examination: lung breath sounds weak, three depressions sign (+, 10 hours died. Pathological examination giant 1.2: Case 1, the liver surface was dark purple, kidneys combined weight 20.4g, clear corticomedullary demarcation, and bilateral adrenal combined weight 8.2g, the brain surface was yellow, I (-. Case 2, right lung bleeding (section solid, dark red, an emphysema (alveolar edge of gray, swollen, floating, dark left lung, bleeding (section solid, dark red, water sink. kidneys combined weight of 19.3 g,