Nifedipine combined stability of the treatment efficacy of 390 cases of renal colic.doc

 PAGE \* MERGEFORMAT 4 Nifedipine combined stability of the treatment efficacy of 390 cases of renal colic [Abstract] Objective: To investigate the stability of nifedipine combined with the clinical effects of treatment of renal colic. Methods: 765 cases of renal colic were randomly divided into two groups, Tramadol and 654  2 standard-dose group (control group) 375 cases, the joint application of nifedipine and stability in the group (treatment group) 390, observing the total effective rate significant efficiency and analgesic onset time. Results: The treatment group and control group, the total effective rates were 80.51% and 60.27%, P amp;lt;0.01. Conclusion: Nifedipine and stability in the treatment of renal colic, with quick, adverse reactions and so on. [Keywords:] nifedipine and stability of renal colic Tramadol 6542 Often a result of renal colic caused by urinary tract obstruction, attack renal prostaglandin synthesis and release increase, resulting in decreased renal vascular resistance, renal blood flow and glomerular filtration increase, and inhibit the secretion of antidiuretic hormone, resulting in urine increase in acute urinary tract stones to ureteral obstruction, the renal pelvis and ureter pressure rapidly increased, smooth muscle spasm, and thus causing renal colic. Nifedipine is a calcium antagonist, through the inhibition of calcium ions into the cell, so that smooth muscle contraction weakened to relieve kidney and ureter spasm; also decreased renal prostaglandin synthesis and secretion, thereby reducing urine output, lower renal pelvis, ureter internal pressure; also has anti-sympathetic effect, can reduce the excitability of the sympathetic nervous system. Stability is a central muscle relaxant, and sedative at the same time, the patient can eliminate fear, anxiety. Combination of two drugs, the role of enhanced so as to achieve rapid analgesic purposes. 1 Data and methods 1.1 General information on 765 cases of patients, 480 case