Non-alcoholic fatty liver in patients with serum adiponectin and TNF-α of.doc

 PAGE \* MERGEFORMAT 2 Non-alcoholic fatty liver in patients with serum adiponectin and TNF-α of Author: Wang Qiang Yu Xiao-mei HU Qin-Xin Ye Xiong-Wei Weng Mei Yu Peng [Abstract] Objective To study the adiponectin and tumor necrosis factor-α (TNF-α ) and non-alcoholic fatty liver disease relationship. Methods Determination of RIA reagents non-alcoholic fatty liver group and control group, adiponectin and TNF-α , using SPSS statistical software to compare and analyze with other conventional indicators of relevance. The results of non-alcoholic fatty liver group of serum adiponectin (5.05 ± 4.47) μ g / ml lower than the control group (8.15 ± 6.48) μ g / ml, the difference was statistically significant (t = 3.56, P amp;lt;0.05); while its TNF-α (1.93 ± 1.09) ng / ml control group (1.28 ± 0.82) ng / ml, the difference was statistically significant (t =- 4.51, P amp;lt;0.05), adiponectin and fasting insulin and negatively correlated with BMI (r = =- 0.26, -0.24, P all amp;lt;0.05), TNF-α and Lnγ -GT positive correlation (r = 0.23, P amp;lt;0.05). Conclusion Non-alcoholic fatty liver may be related to the occurrence of adiponectin and tumor necrosis factor-α in a certain relationship between the abnormal. [Keywords:] non-alcoholic fatty liver adiponectin tumor necrosis factor-α Abstract Objective To investigate serum adiponectin and TNF-α in patients with nonalcoholic fatty liver disease (NAFLD). Methods Serum adiponectin and TNF-α were tested by RIA kits. Difference between two groups and correlation with other routine data were analyzed by SPSS. Results Serum adiponectin level was significantly lower in patient with NAFLD than in control [(5.05 ± 4.47) μ g / ml vs (8.15 ± 6.48) μ g / ml, t = 3.56, P