Non-diabetic patients with metabolic syndrome the change of adiponectin levels and insulin resistance in study.doc
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Non-diabetic patients with metabolic syndrome the change of adiponectin levels and insulin resistance in study
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Non-diabetic patients with metabolic syndrome the change of adiponectin levels and insulin resistance in study
[Abstract] Objective: To observe the non-diabetic metabolic syndrome (MS) patients with serum adiponectin levels, adiponectin levels to understand and insulin resistance. Methods: 92 cases of non-diabetic MS patients and 30 healthy controls, application enzyme-linked immunosorbent assay of serum adiponectin levels and insulin resistance index, insulin sensitivity index. Results: MS serum adiponectin levels were significantly lower than the control group (1.15 +-0.81mg / L vs 4.81 + -1.20 mg / L, P lt;0.01. linear correlation analysis showed that patients with MS, serum adiponectin levels and insulin resistance index was negatively correlated (P lt;0.01, and insulin sensitivity index was positively correlated (P lt;0.01, by multiple linear regression analysis showed that , serum adiponectin levels and insulin resistance index was negatively correlated (P lt;0.01. Conclusion: non-diabetic patients with metabolic syndrome was significantly lower adiponectin levels, serum adiponectin levels and insulin resistance index was significantly negatively correlated, suggesting that serum adiponectin levels and insulin resistance and metabolic syndrome related to the occurrence and development.
[Keywords:] the metabolic syndrome, adiponectin, insulin resistance
Abstract Objective: To study serum adiponectin levels in metabolic syndrome patients (MS) without diabetes and analyse the relationship between serum adiponectin levels and Insulin resistance. Methods: An examination was made among 92 MS patients without diabetes (MS group) and 30 healthy controls. Serum adiponectin level was determined by using enzyme linked immunosorbent assay. Homeostasis insulin resistance index (Homa-IR) and insulin sensitivity index (ISI) were calculated. Results: The serum level of adiponectin was significantly lower in MS group than that in the con
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