NT-brain natriuretic peptide in left ventricular dysfunction diagnosis.doc

 PAGE \* MERGEFORMAT 13 NT-brain natriuretic peptide in left ventricular dysfunction diagnosis Of: Wang Guangyao, Hehan Kang, Jian Chen, Dong Zhou, Han Minghua [Abstract] Objective To investigate the N terminal pro-brain natriuretic peptide (NT-BNP in the diagnosis of heart failure. Methods 81 patients with NYHA , , , -level structural heart disease patients before treatment in the hospital blood pumping elbow , measured by enzyme immunoassay NT-BNP, 36 cases of normal control group, the physical examination, blood testing NT-BNP. Echocardiographic assessment of blood the day of heart failure related to the time index, left ventricular ejection fraction ( LVEF, left ventricular end diastolic diameter and pulmonary artery pressure. Results In the control group, , , , level in patients with structural heart disease the median NT-BNP were 26.6,70,151.2,2724.1,7728.7 pg / ml, NT-BNP on the mean number (1.5 + -0.4, (2 + -0.4, (2.3 + -0.5, (3.3 + -0.6, (3.8 + -0.5, single-factor analysis of variance was significant difference (P lt;0.01, If 256pg/ml critical value for the diagnosis of heart failure, the sensitivity was 97% and specificity of 85%. NT-BNP and NYHA classification of cardiac function indexes correlation coefficient (r = 0.456, P lt;0.01). Diagnosis of left ventricular dysfunction NT-BNP are higher than echocardiography sensitivity and specificity. Conclusions NT-BNP in the diagnosis of left heart failure fast, simple, sensitive and specific indicators can also be used to determine the severity of left heart failure. NT-BNP correlated with pulmonary artery pressure, measured by NT-BNP and the clinical diagnosis of heart and lung disease can provide valuable information. [Keywords:] N terminal pro-brain natriuretic peptide in diagnosis of left ventricular dysfunction Clinical value of N-terminal proBNP in diagnosis of left heart failure WANG Guang-yao, HE Han-kang, CHEN Jian, ZHOU Dong, HAN Ming-hua (Cardiology Department, Liuzhou Tradit