Omental transplantation for treatment of experimental study of femoral head necrosis.docVIP

Omental transplantation for treatment of experimental study of femoral head necrosis Author: Lin Chui-Chung Chen Ronghua Wu Yungang Shen Quan Zhou Wei Ye Chengyu [Abstract] Objective: To investigate the pedicled omental transplantation for treatment of steroid-induced avascular necrosis of the effect. Methods: 9 dogs, the application intramuscular injection of methylprednisolone induced avascular necrosis of animal models, in the first 8 weeks in the C-arm down the right side of the femoral head of pedicled greater omentum transplantation surgery for the experimental group, will be received no treatment contralateral (left) for the respective control side. Contrast to both sides of the femoral head shape, bone structure, bone cells, bone marrow fat cells, bone lacunae, and the capillary number, vessel diameter and ultrastructural changes. Results: The experimental group of non-surgical side of the femoral head with uneven density, with cystic translucent zone, there deformed femoral head, femoral head collapse, femoral head fracture and dislocation of the hip; seen a large number of empty lacunae, the relative reduction in the number of blood vessels, blood vessels become relatively smaller in diameter, marrow hematopoietic cells within the fat reduction and mast cells increased, with a typical bone cell degeneration and necrosis signs. Experimental group was greater omentum transplantation of femoral head lateral capillary a large number of hyperplasia, the formation of network-like, necrotic foci in a large number of new trabecular bone, immature bone cells. Conclusion: The use of C-arm X-ray machine positioned drilling, pedicled omental transplantation can improve the canine steroid-induced avascular necrosis of the femoral head microcirculation and reduce intraosseous pressure, to a certain extent promote the bone repair. Surgical trauma, surgery is simple. [Keywords:] canine femoral head necrosis of the greater omentum transplantation model of hormone Ava