On intravenous thrombolytic therapy for acute cerebral infarction.docVIP

On intravenous thrombolytic therapy for acute cerebral infarction [Abstract] Objective To investigate the thrombolytic treatment of acute cerebral infarction (ACI) of the patients. Methods 48 cases of ACI patients were intravenous thrombolytic therapy, and after treatment 12h, 24h, 48h, 72h and 1 week, 2 weeks respectively NDS (clinical neurological deficit procedure) score, observe the condition. Results 2 weeks after thrombolysis ADL (ADL) score (52.1 + -39.2) than before treatment (17.2 + -21.2) was significantly improved (P lt;0.01), good prognosis, 32 cases basically recovered in 28 cases, significant progress, progress, no change in the 4 cases, deteriorated in 8 cases. Conclusion Intravenous thrombolysis is an effective method for treatment of acute cerebral infarction. [Keywords:] urokinase thrombolysis of acute cerebral infarction Tends to increase in recent years, the incidence of cerebral infarction, age of onset is also earlier than in the past, disability is high, particularly in patients with massive cerebral infarction survivors often left the more serious neurological deficit, the key to their treatment as soon as possible so that occlusion vascular recanalization, the necrotic area around the ischemic penumbra as early as possible by the blood supply to nerve cells, reducing nerve tissue necrosis, reduced infarct size. but the brain of reperfusion, such as more than 6h, the free radical formation, nerve cell calcium overload, release of excitatory amino acids, etc., can increase ischemic nerve tissue damage, this is the reperfusion injury. Therefore, thrombolytic therapy should be strictly limited to within 3-6h in the pathogenesis. our hospital from January 2004 -2009 years December urokinase thrombolytic therapy in patients with acute cerebral infarction in 48 cases, a significant effect, are as follows. 1 Clinical data 1.1 General information on the incidence lt;6h in 48 patients with ACI, in line with the National Conf