On the Adverse Drug Reaction Monitoring of the difficulties.docVIP

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2017-05-08 发布于浙江
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On the Adverse Drug Reaction Monitoring of the difficulties.doc

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On the Adverse Drug Reaction Monitoring of the difficulties

On the Adverse Drug Reaction Monitoring of the difficulties [Abstract] proposed adverse drug reaction monitoring of China’s difficulties, the aim of effective monitoring through improved methods to accurately find the crowd there adverse reactions to promote the drug post-marketing surveillance methods of standardization, improve quality and to promote rational drug prescribing . [Keywords:] Adverse Drug Reaction Monitoring difficulties In recent years, with the scientific and technological development and widespread use of drugs, drug-induced harm is becoming more obvious highlights. According to WHO statistics, the national inpatient rate of adverse drug reactions occur in about 10 ~ 20%, of which 5% of patients because of severe adverse drug reactions and death. The death of patients around the world, about 1 / 3 of patients die from improper medication. Had reported that the U.S. hospitalized patients of serious adverse drug reaction rate was 6.7%, fatal adverse drug reaction rate was 0.32%. In 1994, adverse drug reaction to death of socio-demographic ranking No. 4 cause of death in heart disease, cancer, stroke. Adverse drug reactions have become the focus of attention. An adverse drug reaction (Adverse Drug Reactions; ADR) 1.1 The definition of adverse reaction monitoring work should first correct understanding of adverse drug reactions (adverse drug ractions, referred to as ADR) means, according to WHO Collaborating Center for International Drug Monitoring by definition, adverse drug reaction is’ in the prevention, diagnosis, treatment of disease or regulating physiological function process, acceptance occurs when the normal dose of medication and any adverse drug reactions irrelevant to the purpose ‘. This definition excludes traffic accidents caused by improper medication overdose or adverse reactions. Here should be emphasized that want to monitor adverse drug reactions in the ‘normal usage, normal usage’ appears under the adverse reactions. This w