On the drug-induced kidney disease pathogenesis treatment and prevention of.docVIP

 PAGE \* MERGEFORMAT 8 On the drug-induced kidney disease pathogenesis treatment and prevention of [Paper Keywords] drug-induced kidney disease; pathogenesis; prevention; treatment [Abstract] therapeutic effect of drugs on disease, but the body can cause adverse reactions, or even result in varying degrees of damage, especially to the kidneys. In this paper, drug-induced kidney disease pathogenesis, risk factors, the main clinical manifestations, diagnosis, treatment and prevention of several aspects of the principles set out to remind clinicians cautious, rational use of medicines, control and reduction of adverse drug reactions and side effects place. Kidney as drug metabolism and excretion organs, vulnerable to a variety of drug damage. Drug-induced kidney damage mechanisms vary, but must be caused by clinicians and clinical pharmacists at all levels attach great importance to taking all possible measures to mitigate the damage of drugs to the kidneys. The new synthetic drugs have been developed for clinical treatment offers hope, but because of inadequate attention to the adverse drug reactions, leading to drug-induced kidney damage is increasing. With kidney disease, the continuous improvement of diagnostic techniques and found that by the drug-induced kidney disease there is an increasing trend of domestic and foreign scholars have been attracted great attention. The writer’s drug-induced kidney disease classification, pathogenesis, prevention and treatment are summarized as follows: A common clinical syndrome, There are acute tubular necrosis or acute tubular injury, acute interstitial nephritis, acute renal function before renal failure, obstructive acute renal failure, chronic interstitial nephritis, glomerulonephritis, renal tubular function barriers, renal vascular damage to several categories. 2 Pathogenesis Because of drug-induced nephropathy is the general term for several kinds of clinical syndrome, the different types of drug-indu