Oxaprozin and nimesulide treatment of rheumatoid arthritis efficacy.docVIP

 PAGE \* MERGEFORMAT 7 Oxaprozin and nimesulide treatment of rheumatoid arthritis efficacy Abstract Objective oxaprozin and nimesulide treatment of rheumatoid arthritis, the efficacy and adverse reactions. Methods 120 cases of oxaprozin 400mg, 90 nimesulide po, daily morning and evening services 0.1g. Results po nimesulide group of patients with total effective rate was 73.78%, the efficacy of oxaprozin and nimesulide similar and relatively low incidence of adverse reactions. Keywords: oxaprozin nimesulide rheumatoid arthritis Rheumatoid arthritis (rheumatoid arthritis RA) is a kind of chronic progressive disease characterized by synovial systemic autoimmune diseases. The pathology is characterized by lymphocyte infiltration of inflammatory cells such as synovitis and vasculitis caused [1] . Oxaprozin (brand name Oraprozin Tabets abbreviation: OXP) The chemical name of 4.5-diphenyl oxazole -2-- acid. It is an inhibitor of prostaglandin cyclooxygenase and inhibit biosynthesis of new non-steroidal anti-inflammatory, antipyretic and analgesic drugs. The symptoms of rheumatoid arthritis, ankylosing spondylitis, and pain, fever and other diseases. We oxaprozin treatment of RA and osteoarthritis (osteoarthosis OA) and with the positive control drug nimesulide (4 - nitro -2-- phenoxy benzene sulfonyl methane) were random effects and adverse reactions. 1 Materials and Methods 1.1 Case Selection: RA diagnosis according to American Rheumatism Association (ARA) 1987 years of diagnostic criteria, the main choice of active RA patients. Diagnosis of OA based on a typical X-ray findings. Compared patients with no active or history of recurrent ulcers, no serious heart, liver, lung, kidney and other organ diseases and drug allergies. Were randomly divided into 2 groups. OXP group of 170 cases, 75 cases of male and 95 females, age (60 + -15) y. Male 50, female 65 cases, age (60 + -14) y. In comparing the pre 3wk immunosuppressants use