Panangin gold Clinical efficacy of treatment of diabetes.docVIP

 PAGE \* MERGEFORMAT 6 Panangin gold Clinical efficacy of treatment of diabetes [Keywords:] Panangin Gold diabetes observed Magnesium as a trace element the human body, and diabetes are closely related, we have: 1 July 2008 by Panangin gold (potassium magnesium aspartate) in the treatment of diabetes to obtain a certain effect. These are as follows: Choice of cases: diabetes mellitus by WHO in 1980, the second meeting of the Committee of Experts report on diagnostic criteria, diagnosed with diabetes type , and has been taking glibenclamide, phenformin or gliclazide and other drugs are not satisfied with the treatment of blood glucose control were 25 ( male 14, female 11), duration of 5 to 11 years, age 37 to 70 years, no renal damage. ACTION: aspartic acid as the potassium and magnesium carrier, so that K +, Mg2 + is easy and cell membrane, triggering membrane K +-Na +-ATP enzyme, Ca2 +-ATP activity, the K +, Mg2 + ions are easy to enter the cell. Magnesium is the cell number of cofactor, involved in oxidative phosphorylation and ATP and creatine phosphate formation, thereby improving the cellular energy metabolism. Mg2 + can regulate cardiac Ca2 + channels, K + channels and CI-channel in order to maintain the film on both sides normal ion distribution and membrane potential. magnesium can antagonize calcium. aspartate in Sansuo cycle and ornithine cycle in which ammonia and carbon dioxide with formation of urea. Pharmacology and toxicology: magnesium and potassium ions are important intracellular cation. They play for the function of many enzymes essential role in the subcellular macromolecules can be combined with muscle contraction on the mechanism related. Contractility of myocardial cells by the cell, extracellular potassium, calcium, sodium concentration ratio. in the use of cardiac glycosides during treatment, the drug caused by treatment can be used to compensate for the skeletal muscle, cardiac muscle, plasma, erythrocyte magnes