Papaya Tablets by High Performance Liquid Chromatography content of China-EU imperatorin.docVIP

 PAGE \* MERGEFORMAT 10 Papaya Tablets by High Performance Liquid Chromatography content of China-EU imperatorin Author: Ye Ting Xiang Liu Zheng-Hui Zhao Hongzhi Liu Xinyuan Li Cheng Yi Luo Guoan [Abstract] Objective To establish a Central Imperatorin papaya tablets by high performance liquid chromatography (HPLC) assay method. Method column was Agilent Eclipse XDB C18 column (4.6 mm * 250 mm, 5 μ m); mobile phase was methanol - water (59:41); flow rate of 1.0 ml / min; wavelength of 248 nm, column temperature was 30 ℃ . Results Imperatorin linear range of 5.64 ~ 56.4 mg (r = 0.999 4); average recoveries were 97.8% (RSD 1.65%). Conclusion The specificity of quantitative methods to build strong, reproducible, papaya tablets for quality control methods. [Keywords:] papaya tablets; Imperatorin; high-performance liquid chromatography; Angelica Abstract: ObjectiveTo establish the quality standard for Mugua Tablets. MethodsThe content of Imperatorin was determined by HPLC. The chromatographic column was an Agilent Eclipse XDB C18 (4.6 mm * 250 mm, 5 mm), the mobile phase was methanol-water (59: 41), the detection wavelength was 294 nm, the flow rate was 1.0 ml / min, and the column temperature was 30 ℃ . ResultsThe linear ranges of imperatorin were with in the range of 5.54 to 56.4mg (r = 0.999 4). The average recovery was 97.8% (RSD was 1.65%). ConclusionThe HPLC method is exclusive, reproducible and suitable for the quality control of Mugua Tablets. Keywords:: Mugua Tablets; Imperatorin; HPLC; Radix Angelicae Dahuricae Papaya tablets contained in the closed ministerial Drug Standards (WS3-B-1890-95), from papaya, Chinese angelica, Chuanxiong, Angelica and other 12 Chinese herbal flavor composition, mainly for wind cold dampness weakness, limb numbness, vague aches and pains, waist and knee weakness , moving forward with difficulty. Angelica-based medicine Fang, one of the main group, which contain chemical constituents in volatile oil, coumarin-based, with sc