Pharmacological effects of gypsum.doc

 PAGE \* MERGEFORMAT 7 Pharmacological effects of gypsum [Keywords:] cast the role of 1. Antipyretic effect of artificial heating of gypsum has some antipyretic effects animals. Decoction 1:1 with gypsum and rectal administration, determination of cattle or rabbit fever caused by typhoid vaccine effects, the results show a certain degree of cooling effect no effect of pure calcium sulfate. Another use of gypsum or plaster of Paris reported an infusion 10g/kg fed on artificial fever in rabbits also have a slight cooling effect, but no effect on normal body temperature. on the typhoid fever vaccine in rabbits caused 5g / kg and 0.2g/kg gypsum cooling effect similar to aspirin for safety, to serve the half-hour after the temperature dropped significantly, from 1 to 1.5 hours in the strongest, so that the plaster has a rapid but short duration of the antipyretic effect. Gypsum has also been reported by injection decoction 15g/kg feeding on typhoid fever caused by pentavalent vaccine was no cooling effect in rabbits, as rabbits fed gypsum give decoction 15g/kg, and then injected with five typhoid vaccines can not cause the body temperature associated greatly increased. gypsum no cooling effect on normal body temperature, but obviously artificial cooling effect of rabbit fever, and its cooling effect may not be the main component because of the role of calcium. Some of the gypsum powder produced in Hubei Province to give typhoid bacteria Miao cause fever in rabbits, the results of the decoction or 20g/kg 20g/kg plus 2g/kg gypsum powder decoction were no significant cooling effect, 20 cases of clinical observation of patients with fever, a decoction of oral 40ml 1:1 , 4 hours, there was no cooling effect, so that the gypsum does not have antipyretic effects. Foreign usefulness of experimental fever in rats proved, gypsum gavage, subcutaneous injection or intravenous antipyretic though not see a clear role, but When to prohibit drinking, LPS cause fever, give diuret