Pharmacological effects of licorice soil.doc

 PAGE \* MERGEFORMAT 9 Pharmacological effects of licorice soil Of: Guo Li City, Yang love, Yusheng Min, Huang Linyun, Chen Shaofeng [Abstract] Objective of the soil water extract and licorice ethanol extract of the anti-inflammatory and analgesic effect and acute toxicity studies. Methods xylene-induced mouse ear edema, acetic acid soil licorice observed anti-inflammatory, analgesic effect of aqueous extract of licorice root to soil 1.57 g ml-1, ethanol extract of 2.40 g ml-1, the maximum dose of 40 ml kg-1 mice were orally administered to observe the acute toxicity. Results Soil Licorice on ear swelling induced by xylene in mice significantly inhibited (P lt;0. 05, of 0.7% acetic acid induced writhing response in mice significantly inhibited (P lt;0.05. soil aqueous extract of licorice mice by administration of the maximum tolerated dose was 62.8 g crude drug kg-1, ethanol extract the maximum tolerated dose of oral administration in mice is 96.0 g amount of crude drug kg-1. Conclusion licorice has some soil anti-inflammatory and analgesic effects, soil water extract and licorice extract alcohol does not appear other toxic reactions. [Keywords] soil licorice, pharmacology, acute toxicity Zhuang medicine for the legume licorice soil trichocarpa Derris Derris eriocarpa How dry root, vine, also known as “Millettia” “vine licorice,” and so on, located in Guangxi, Yunnan area. Root medicine, blood, intestines, with in fever, chest tightness, cough, sore throat, rattan medicine, diuretic dehumidification, cough and phlegm, for urination pain, cough, edema. hemoptysis folk commonly used in cough embolism. so far in the domestic public offering of journals , only on its raw pharmaceutical research, no research on soil licorice pharmacology and toxicology data. for further research and development and clinical application of experimental evidence, the paper launched its anti-inflammatory, analgesic efficacy and acute toxicity of the role. 1 Materials