Plasmapheresis Detection of serum cholinesterase activity.doc

 PAGE \* MERGEFORMAT 7 Plasmapheresis Detection of serum cholinesterase activity [Abstract] Objective To investigate the serum cholinesterase (ChE in the plasma exchange and clinical significance of changes before and after. Methods of automatic biochemical analyzer, Hitachi, our hospital patients with plasma exchange therapy in 11 patients (including 9 cases of severe hepatitis B, 2 cases of organophosphate poisoning, blood testing before and after the replacement of ChE activity. Results The preoperative mean ChE activity (3 118.4 +-538.6U / L, replacement of ChE activity after a mean (4 996.2 +-625.3U / L, by the statistics chemical treatment, the difference was statistically significant (t = 7.546, P lt;0.01. Conclusion ChE activity increased significantly after plasma exchange, dynamic observation of ChE activity levels can be used as organophosphate poisoning, hepatitis B patients with severe disease to determine, predict prognosis The sensitivity and reliability. [Keywords:] plasma exchange, cholinesterase, organophosphate poisoning, severe hepatitis B [Abstract] Objective To investigate the change and its clinical significance of the serum cholinesterase before and after plasma exchange (PE. Methods 11 cases (9 cases with severe hepatitis B and 2 with organic phosphate poisoning) were phlebotomized before and after PE to check the ChE by Hitachi auto biochemical analyzer. Results The average ChE is (3 118.4 +-538.6U / L before PE and (4 996.2 +-625.3U / L after it.The difference had statistical significance (t = 7.546, P lt;0.01. Conclusion The serum cholinesterase activity rises obviously after PE.The dynamic observation to the change of ChE level can be regarded as a sensitive and reliable index to judge the pathogenetic condition and forecast turnover of the patients with organic phosphate poisoning or severe hepatitis B. [Keywords:] Plasma exchange, Cholinesterase, Organic phosphate poisoning, Severe hepatitis B Plasma exchange is one