Pneumonia and neonatal serum levels of dipeptidyl peptidase detection and immunological evaluation of the value of.doc

 PAGE \* MERGEFORMAT 12 Pneumonia and neonatal serum levels of dipeptidyl peptidase detection and immunological evaluation of the value of Of: Li Zheng, Lu Xianmei, Liu Yan, Jing Ti Deng, Li [Abstract] Objective To detect pneumonia neonatal serum dipeptidyl peptidase (DPP Ⅳ / CD26 levels and to investigate its value in the immune evaluation in order to find sensitive and reliable evaluation of neonatal immunity. Methods immune assay for measuring the pneumonia group ( 64 cases and the control group (30 cases of serum DPP Ⅳ / CD26 levels were measured in T cells and subsets (CD3 + T%, CD4 + T%, CD8 + T% and immunoglobulin (IgG) levels. Results pneumonia Serum DPP Ⅳ / CD26 was significantly lower than the control group (P lt;0.01, and with the CD3 + T%, CD4 + T% and was positively correlated with age. Conclusion Serum DPP Ⅳ / CD26 T cell subsets compared with (CD3 + T% , CD4 + T%, CD8 + T%, and IgG is more sensitive, as neonatal immune evaluation. [Keywords:] newborn, pneumonia, dipeptidyl peptidase, T cell subsets, immunoglobulin, immune [Abstract] Objective To investigate the level and influential factors of dipeptidyl peptidase Ⅳ / CD26 (DPP Ⅳ / CD26in serum of neonates with pneumonia in order to offer a sensitive index evaluating the immune function of nenates.Methods Colorimetric method was employed to detect DPP Ⅳ / CD26 in the pneumonia group (64 cases) and control group (30 cases). T cell subset (CD3 + T, CD4 + T, CD8 + T and immunoglobulin (IgG) were also detected.Results The level of DPP Ⅳ / CD26 in the pneumonia group was significantly lower than the control group (P lt;0.01and shew a positive correlation with CD3, CD4 and age.Conclusion DPP Ⅳ / CD26 is much more sensitive than T cell subset (CD3 + T, CD4 + T, CD8 + T and immunoglobulin (IgG) and can be used to evaluate the immune level of neonates. [Keywords:] infant, newborn; pneumonia; dipeptidyl peptidase Ⅳ / CD26; T cell subset; immunoglobulin; immune For a long time, people will