Polygonatum Extract on Mice hypoxia - reoxygenation injury in rats.docVIP

 PAGE \* MERGEFORMAT 6 Polygonatum Extract on Mice hypoxia / reoxygenation injury in rats Authors: Wende Jian, Chen Guodong, Zhu Yun-chao, ZHANG Cui-lan, XIAO this see [Abstract] Objective To investigate the Polygonatum extract on mice hypoxia / reoxygenation injury in rats. Methods The mice were Polygonatum extract treatment, the establishment of mouse hypoxia / reoxygenation injury model of the blood of mice in the ROS, SOD, MDA and other changes. Results of Polygonatum extract can reduce the mouse ROS and MDA values, enhance the SOD activity of the CAT is not obvious. Conclusion Polygonatum extract of mouse hypoxia / reoxygenation lipid peroxidation has a protective effect. [Keywords:] Polygonatum extract hypoxia / reoxygenation of reactive oxygen species superoxide dismutase MDA catalase; acid phosphatase Liliaceae Polygonatum Phellodendron genus species of plants of dry roots, a kidney, Ziyin Runzao of power, for nourishing and treatment of kidney essence and physical losses, lung deficiency dry cough and weakness of the spleen and stomach disorders [1], there a very long history, is one of Chinese medicine commonly used drugs. Growth in Hubei Enshi Se (Enshi is China’s high-selenium area) mountain jungle yellow essence, because of its efficacy Se Ershi unique and significant effect. In this experiment, mice were studied to establish hypoxia / reoxygenation injury in the model, the main research Polygonatum extract of mouse hypoxia / reoxygenation injury in rats, in order to Polygonatum clinical application and further research and development and provide a theoretical basis and reference. 1 Materials 1.1 herbs Polygonatum purchased the company in Enshi Chinese herbal medicines, using dual-channel beam atomic fluorescence spectrometry for selenium content of 0.58 μ g / g. 1.2 Animals 30 Kunming mice, weighing 18 ~ 22 g, ♂ ♀ use either by the Experimental Animal Center of Tongji Medical University. 1.3 reagent reactive oxygen species (ROS) detecti