Power for obesity on leptin insulin resistance.docVIP

 PAGE \* MERGEFORMAT 9 Power for obesity on leptin insulin resistance [Abstract] Objective To observe the power of serum leptin for obesity (Leptin) and insulin (INS) levels, obese rats of acupuncture on fat, the mechanism of lipoprotein metabolism. Methods SD rats were randomly divided into normal group , model group, EA group, drug group. normal group fed with normal diet, according to requirements of the other groups fed high fat diet, making film after 4 weeks, double-EA “in customs,” double “Zusanli” points. Leptin serum by ELISA, the content of radioimmunoassay of serum INS levels. Results EA group decreased body weight in obese rats, serum Leptin, INS levels were significantly decreased, compared with the model group were significantly different (P lt;0.05), drug group Compared with model group were significantly different (P lt;0.05). Conclusion Electroacupuncture in obese rats with a weight loss effect, can reduce obesity, serum Leptin, INS levels, and promote fat metabolism and improve the Leptin receptor, INS receptor sensitivity and expression, activation of signaling lipid-lowering diet may be the acupuncture study important cellular and molecular mechanisms. [Keywords:] acupuncture, obesity, leptin, insulin, rat Abstract: Objective To observe the effect of electronic acupuncture on serum leptin and insulin of rats with simple obesity. Methods SD rats were randomly divided into normal group, model group, electronic acupuncture group and western medicine group. The normal group were fed with normal feedstuff , while the other rats were all fed with a fat-rich diet. Four weeks after modeling, bilateral Neiguan and Zusanli acupoints were punctured with electronic acupuncture. Serum leptin content was detected with ELISA, insulin with radio-immunity. Results With acupuncture, the weight was lost, at the same time, the levels of the serum leptin and insulin of obesity rats decreased significantly in the electronic acupuncture group compared wit