Preparation of Spleen Yiwei granules Process and Quality Control.docVIP

Preparation of Spleen Yiwei granules Process and Quality Control.doc

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Preparation of Spleen Yiwei granules Process and Quality Control

 PAGE \* MERGEFORMAT 8 Preparation of Spleen Yiwei granules Process and Quality Control [Abstract] Objective: To investigate the spleen Yiwei granule preparation process and the development of its quality control standards. Methods: Preparation of water-purification Shen granules to each other in the thin-layer chromatography for identification of white peony with red peony, using high performance liquid chromatography granules of paeoniflorin were determined. Results: Radix Paeoniae Rubra, Radix Paeoniae Alba board spots clear, high-performance liquid chromatography measured the total paeoniflorin content 32.181mg / g. Conclusion: The granule preparation process is reasonably practicable, identification method is reliable and can be used for quality control of the particle. [Keywords:] spleen Yiwei particle; preparation process; quality standard Yiwei particles in the spleen under the guidance of TCM theory, in order to spleen Huashi, Huayu the principle of compatibility of lipid-lowering medicines for the treatment of Chinese herbal compound formed by the red peony, white peony root, Chinese yam, Alisma, Scrophulariaceae taste of drugs such as 5 composition, for the spleen and stomach function disorders caused by diseases such as chronic gastritis. Process according to modern traditional Chinese medicine preparation methods and quality control principles, to study the granule preparation process and the establishment of quality control, the report is as follows. An experimental material 1.1 The medicines and reference substance Medicinal herbs were purchased from Guangzhou Qingping market, was identified as a genuine medicine. Paeoniflorin reference substance, Lot 10736  200527, China Pharmaceutical and Biological Products Institution, for the determination and identification of use. 1.2 Reagents Silica gel G, carboxymethyl cellulose were purchased from Qingdao Marine Chemical Factory 20,080,708; chloroform, ethyl acetate, methanol, formic acid, cyc

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