Prognostic factors in bladder cancer Cox proportional hazards analysis.docVIP

 PAGE \* MERGEFORMAT 11 Prognostic factors in bladder cancer Cox proportional hazards analysis Of: Nan Yong, SPECTROSCOPY AND ZHAO Jing-new, Zhang, Zhou Sun House [Abstract] Objective To investigate the surgical treatment of bladder cancer prognostic factors. Methods Retrospective analysis of 115 cases of surgical treatment of the clinical data of patients with bladder cancer were followed up for 1-5 years, using Cox proportional hazards model for univariate and multivariate analysis, Kaplan Comparison-Meire survival between different groups, Log Rank test. Results Univariate analysis showed: bladder cancer and tumor size (OR = 1.923, P = 0.045), histological grade (OR = 0.2.252, P = 0.001), tumor stage (OR = 2.010, P = 0.002), surgical procedure (OR = 2.230, P = 0.001), postoperative bladder (OR = 0.407, P = 0.020), pelvic lymph node status (OR = 3.522, P = 0.001), invasion (OR = 2.549, P = 0.015) correlation; multivariate analysis: After bladder irrigation, pathological grade, tumor stage, pelvic lymph node status, depth of infiltration into the Cox regression model. Conclusion bladder cancer prognosis with a number of factors, protective factors are bladder perfusion, low histological grade, tumor stage are high, the bladder and surrounding lymph node infiltration in 5-year survival rate was significantly decreased. bladder for invasive and associated with lymph nodes metastasis are advised to radical cystectomy, in order to prolong the survival period, is expected to improve the prognosis of bladder surgery. [Keywords:] Bladder cancer; risk factors; Cox regression analysis; prognosis Long-term survival of patients with bladder cancer complex factors, one factor is often difficult to predict. Patient survival and prognostic factors of clinical report significantly different results. We applied Cox proportional hazards regression model analysis of 115 cases of bladder cancer, the survival of patients factors to be targeted for early intervention a