Progress in pathological diagnosis of pleural mesothelioma.docVIP

 PAGE \* MERGEFORMAT 12 Progress in pathological diagnosis of pleural mesothelioma Keywords: Pathological diagnosis of pleural mesothelioma Pleural Mesothelioma is a rare tumor, but its incidence in recent years, an increasing trend year by year. As the potential for differentiation between the multi-function leather resulted in a variety of malignant mesothelioma cell morphology, in the light microscope, with pleural metastatic adenocarcinoma, reactive mesothelial cells and other spindle cell tumors is not easy to identify, to work with clinical and pathological diagnosis of to the difficulties. Of pleural mesothelioma in recent years due to the level of awareness raising and electron microscopy, immunohistochemistry technology, so that the diagnosis of pleural mesothelioma has been greatly improved. A light microscope examination As the diversity of mesothelioma cell morphology by light microscopy histological types of malignant mesothelioma is not yet uniform. World Health Organization has to diffuse malignant mesothelioma (dMM) is divided into epithelial, sarcoma, and mixed. adams, etc. 〔 1〕 pleural dMM according to the autopsy material is divided into epithelioid tumor type, tubular papillary type, sarcomatoid type, myxoid type, desmoid tumor-like type and mixed type. And to propose in Diffuse pleural tumors, such as found in tumor cells to produce collagen material can determine the dMM. Otherwise, there should be a small vacuoles within the cytoplasm and uniform light to moderate nuclear / cytoplasm ratio. In the United States and a 〔 2〕 arrangement according to the tumor cells, tumor cell differentiation and a tumor cell components of different accounts for at least 50% of the tumors were divided into 11 types: tubular-like type, tubular papillary type, undifferentiated type , fibroblast cell type, signet-ring-like cell type, myxoid type, myofibroblastic cell type, lymphatic tissue-like type, vascular mother cell type, small cell type and mixed ce